Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 3/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871532 | 0.83 | NPC1 (0.59) | MAPTRAB9AALDH1A1NPC1LMNA | |
| SCHEMBL10872044 | 0.79 | TSHR (0.54) | L3MBTL1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10656937 | 0.78 | TSHR (0.59) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL9685245 | 0.76 | MAPT (0.58) | L3MBTL1MAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL20042582 | 0.76 | SMN1; SMN2 (0.56) | L3MBTL1MAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8130313 | 0.74 | UBE2N (0.45) | L3MBTL1MAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7629413 | 0.74 | L3MBTL1 (0.66) | L3MBTL1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7632695 | 0.73 | L3MBTL1 (0.74) | L3MBTL1MAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8172219 | 0.73 | L3MBTL1 (0.74) | L3MBTL1MAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL10871644 | 0.72 | CDYL2 (0.59) | MAPTSMN1; SMN2RAB9ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466408-B1 | N-aryl-3-aryl-4-substituted-4,5-dihydro-1H-pyrazole-1-carboxamides and processes for their production | ROHM & HAAS (US) | 2000-01-12 | — | — | EP | disclosed |
| US-5798311-A | INSECTICIDES | ROHM AND HAAS COMPANY (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0466408-A1 | N-aryl-3-aryl-4-substituted-4,5-dihydro-1H-pyrazole-1-carboxamides and processes for their production | ROHM AND HAAS COMPANY (US) | 1992-01-15 | — | — | EP | disclosed |