Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122236 | 0.92 | HTR6 (0.50) | HTR6KDM4ELMNAPOLBHTR1A | |
| SCHEMBL7255363 | 0.72 | HTR6 (0.58) | HTR6KDM4ELMNAPOLBHTR1A | |
| SCHEMBL3336465 | 0.71 | HTR6 (0.74) | HTR6DRD2 | |
| SCHEMBL8344859 | 0.71 | QDPR (0.49) | — | |
| Bromide SCHEMBL9325716 | 0.71 | HTR6 (0.57) | HTR6KDM4ELMNAPOLBHTR1A | |
| SCHEMBL7480892 | 0.69 | NOS3 (0.68) | SLC6A4 | |
| SCHEMBL1673482 | 0.68 | HTR6 (0.54) | HTR6KDM4ELMNAPOLBHTR1A | |
| SCHEMBL13647405 | 0.68 | QDPR (0.40) | HTR6KDM4EALDH1A1GAA | |
| SCHEMBL1720553 | 0.68 | SLC6A4 (0.72) | HTR6KDM4ELMNAPOLBHTR1A | |
| Hydrochloric Acid SCHEMBL1148906 | 0.67 | QDPR (0.65) | HTR6KDM4ELMNAPOLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975593-A1 | INDOLE DERIVATIVES HAVING COMBINED 5HT1A, 5HT1B AND 5HT1D RECEPTOR ANTAGONIST ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998050358-A1 | INDOLE DERIVATIVES HAVING COMBINED 5HT1A, 5HT1B AND 5HT1D RECEPTOR ANTAGONIST ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |