Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 4/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27195861 | 0.79 | QDPR (0.50) | QDPRMMP2MMP3PLK1PLK3 | |
| SCHEMBL8345083 | 0.76 | QDPR (0.54) | QDPRMMP2MMP3 | |
| SCHEMBL8130409 | 0.71 | HTR6 (0.53) | — | |
| SCHEMBL13483657 | 0.71 | MAPT (0.55) | CTSS | |
| SCHEMBL8915112 | 0.71 | QDPR (0.62) | QDPR | |
| SCHEMBL24670132 | 0.71 | MAPT (0.41) | QDPRMMP2MMP3WDR5 | |
| SCHEMBL8346983 | 0.70 | CTSS (0.48) | CTSSPIK3CA | |
| SCHEMBL24669373 | 0.69 | SOS1 (0.49) | WDR5 | |
| SCHEMBL8613848 | 0.69 | QDPR (0.46) | QDPR | |
| SCHEMBL8122236 | 0.68 | HTR6 (0.50) | QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |