SCHEMBL813089

SCHEMBL813089

[C-]#[N+]C(C#N)=C(c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.37
MAPT P10636 3/20 0.37
WDR5 P61964 1/20 0.37
RAB9A P51151 2/20 0.37
LMNA P02545 2/20 0.37
HIF1A Q16665 2/20 0.37
FFAR1 O14842 1/20 0.37
CYP1A2 P05177 1/20 0.37
NPC1 O15118 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
MMP3 P08254 1/20 0.34
BCL2L1 Q07817 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
PTPN1 P18031 1/20 0.34
GSK3B P49841 1/20 0.34
CDC25B P30305 1/20 0.33
ATM Q13315 1/20 0.33
CYP19A1 P11511 1/20 0.33
DHODH Q02127 1/20 0.33
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL813201 0.92 CYP1A2 (0.46) SMN1; SMN2MAPTLMNACYP1A2L3MBTL1
SCHEMBL12939896 0.92 SMN1; SMN2 (0.37) SMN1; SMN2MAPTRAB9ALMNANPC1
SCHEMBL10453518 0.89 MKNK1 (0.36) SMN1; SMN2MAPTRAB9ALMNAHIF1A
SCHEMBL812927 0.89 CYP19A1 (0.37) MAPTRAB9ALMNACYP1A2L3MBTL1
SCHEMBL812937 0.88 CES2 (0.40) SMN1; SMN2MAPTPTPN1ALDH1A1HPGD
SCHEMBL813095 0.88 RAB9A (0.42) MAPTRAB9ANPC1CTDSP1ALDH1A1
SCHEMBL813397 0.83 ALDH1A1 (0.46) SMN1; SMN2MAPTWDR5CYP1A2MMP3
SCHEMBL812936 0.79 CES2 (0.43) SMN1; SMN2MAPTRAB9ALMNANPC1
SCHEMBL812896 0.78 ALDH1A1 (0.37) SMN1; SMN2MAPTRAB9ALMNANPC1
SCHEMBL9068811 0.75 SMN1; SMN2 (0.43) SMN1; SMN2MAPTWDR5RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 US disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 US disclosed
US-9348177-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-9195090-B2 Polymer film, optically-compensatory film, process for producing the same, polarizing plate and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-11-24 US disclosed
US-20150309348-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2015-10-29 US disclosed
US-9097837-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2015-08-04 US disclosed
US-9091804-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2015-07-28 US disclosed
US-20140377528-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
US-8823909-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-7318951-B2 Retardation film, producing process thereof and liquid crystal display utilizing the same FUJIFILM CORPORATION (JP) 2008-01-15 US disclosed
US-20070292635-A1 Optical Compensation Polarizing Plate, Image Display Unit and Liquid Crystal Display Unit FUJIFILM CORPORATION (JP) 2007-12-20 US disclosed
US-20070285603-A1 Transparent Film And Optical Compensatory Film, Polarizing Plate And Liquid-Crystal Display Device Employing It FUJI PHOTO FILM CO., LTD. (JP) 2007-12-13 US disclosed
US-20070273815-A1 Cellulose acylate film, production method of cellulose acylate film, optically-compensatory film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2007-11-29 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070092663-A1 Cellulose ester film, polarizing plate and display KONICA MINOLTA OPTO, INC. 2007-04-26 US disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed
US-20070048458-A1 Optical film, method of producing the same, optical compensatory film, polarizing film, and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-01 US disclosed
US-20070040962-A1 Optical resin film and polarizing plate and liquid crystal display using same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 US disclosed