SCHEMBL813397

SCHEMBL813397

[C-]#[N+]/C(C#N)=C(/c1ccc(-c2ccccc2)cc1)c1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
HPGD P15428 3/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MAPT P10636 3/20 0.38
HTT P42858 2/20 0.38
HSP90AA1 P07900 1/20 0.38
NR4A1 P22736 1/20 0.37
NR4A2 P43354 1/20 0.37
NR4A3 Q92570 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CDC25B P30305 2/20 0.34
BACE1 P56817 2/20 0.33
ACP3 P15309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL813089 0.83 SMN1; SMN2 (0.37) ALDH1A1HPGDSMN1; SMN2CYP1A2MAPT
SCHEMBL9068807 0.82 ALDH1A1 (0.51) ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C9
SCHEMBL812937 0.78 CES2 (0.40) ALDH1A1HPGDSMN1; SMN2MAPTMEN1
SCHEMBL813201 0.76 CYP1A2 (0.46) HPGDSMN1; SMN2CYP1A2MAPTHTT
SCHEMBL12939896 0.76 SMN1; SMN2 (0.37) ALDH1A1HPGDSMN1; SMN2MAPTHTT
SCHEMBL10453518 0.74 MKNK1 (0.36) ALDH1A1SMN1; SMN2CYP1A2MAPTHTT
SCHEMBL813095 0.73 RAB9A (0.42) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL812927 0.73 CYP19A1 (0.37) ALDH1A1CYP1A2CYP2C9CYP2C19MAPT
SCHEMBL14064027 0.72 NR4A1 (0.47) ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2C9
SCHEMBL812936 0.71 CES2 (0.43) ALDH1A1HPGDSMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 US disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 US disclosed
US-9348177-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-9195090-B2 Polymer film, optically-compensatory film, process for producing the same, polarizing plate and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-11-24 US disclosed
US-20150309348-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2015-10-29 US disclosed
US-9097837-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2015-08-04 US disclosed
US-20140377528-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
US-8823909-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-20140055732-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2014-02-27 US disclosed
US-7318951-B2 Retardation film, producing process thereof and liquid crystal display utilizing the same FUJIFILM CORPORATION (JP) 2008-01-15 US disclosed
US-20070292635-A1 Optical Compensation Polarizing Plate, Image Display Unit and Liquid Crystal Display Unit FUJIFILM CORPORATION (JP) 2007-12-20 US disclosed
US-20070285603-A1 Transparent Film And Optical Compensatory Film, Polarizing Plate And Liquid-Crystal Display Device Employing It FUJI PHOTO FILM CO., LTD. (JP) 2007-12-13 US disclosed
US-20070273815-A1 Cellulose acylate film, production method of cellulose acylate film, optically-compensatory film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2007-11-29 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070092663-A1 Cellulose ester film, polarizing plate and display KONICA MINOLTA OPTO, INC. 2007-04-26 US disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed
US-20070048458-A1 Optical film, method of producing the same, optical compensatory film, polarizing film, and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-01 US disclosed
US-20070040962-A1 Optical resin film and polarizing plate and liquid crystal display using same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 US disclosed