SCHEMBL813128

SCHEMBL813128

S=C(SSCCCCCCSSC(=S)N(Cc1ccccc1)Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.71
ALDH1A1 P00352 7/20 0.58
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
ALDH2 P05091 2/20 0.41
GAA P10253 1/20 0.41
FAAH O00519 1/20 0.39
NPSR1 Q6W5P4 2/20 0.39
LMNA P02545 2/20 0.38
RECQL P46063 1/20 0.38
CA12 O43570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23927809 1.00 MGLL (0.71) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL23927811 1.00 MGLL (0.71) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL21947395 1.00 MGLL (0.71) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL23927812 1.00 MGLL (0.71) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL29677145 1.00 MGLL (0.71) MGLLALDH1A1HDAC3HDAC4HDAC1
Hydrogen Sulfide SCHEMBL15021803 0.98 MGLL (0.69) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL23927810 0.98 MGLL (0.73) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL29677031 0.95 MGLL (0.73) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL15048865 0.93 MGLL (0.61) MGLLALDH1A1HDAC3HDAC4HDAC1
SCHEMBL22749487 0.93 MGLL (0.61) MGLLALDH1A1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1077 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055258-A1 A RUBBER COMPOUND MIXTURE KARGRO RECYCLING B V (NL) 2026-02-26 US claimed
US-12516181-B2 Sulphur-crosslinked rubber mixture and vehicle tire CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2026-01-06 US claimed
US-20250197614-A1 RUBBER COMPOSITION FOR TIRE TREAD THE GOODYEAR TIRE & RUBBER COMPANY 2025-06-19 US claimed
EP-4558558-A1 A RUBBER COMPOUND MIXTURE Kargro Recycling B.V. (NL) 2025-05-28 EP claimed
US-20240294557-A1 ORGANOSILYL POLYSULFIDES, AND RUBBER MIXTURES CONTAINING SAME LANXESS DEUTSCHLAND GMBH (DE) 2024-09-05 US claimed
US-20240270939-A1 ORGANOSILYL POLYSULFIDES AND RUBBER MIXTURES CONTAINING SAME LANXESS DEUTSCHLAND GMBH (DE) 2024-08-15 US claimed
US-12054602-B2 Article, in particular air spring bellows, a metal-rubber element, or a vibration damper CONTITECH LUFTFEDERSYSTEME GMBH (DE) 2024-08-06 US claimed
CN-118408895-A Method for testing appearance color change of sizing material 浦林成山(山东)轮胎有限公司 2024-07-30 CN claimed
US-20240239990-A1 ORGANOSILYL POLYSULFIDES, AND RUBBER MIXTURES CONTAINING SAME LANXESS DEUTSCHLAND GMBH (DE) 2024-07-18 US claimed
US-20240199859-A1 RUBBER COMPOSITION FOR TIRE TREAD THE GOODYEAR TIRE & RUBBER COMPANY 2024-06-20 US claimed
WO-2013182610-A2 RUBBER BLENDS CONTAINING SILICIC ACID AND COMPRISING ADDITIVES CONTAINING SULPHUR LANXESS DEUTSCHLAND GMBH (DE) 2013-12-12 WO claimed
WO-2013182594-A2 RUBBER BLENDS CONTAINING SILICIC ACID AND COMPRISING ADDITIVES CONTAINING SULPHUR LANXESS DEUTSCHLAND GMBH (DE) 2013-12-12 WO claimed
EP-2671727-A1 Rubber mixtures containing silicic acids with additives containing sulphur LANXESS Deutschland GmbH (DE) 2013-12-11 EP claimed
EP-2671726-A1 Rubber mixtures containing silicic acids with additives containing sulphur LANXESS Deutschland GmbH (DE) 2013-12-11 EP claimed
EP-2607100-A1 Tire rubber composition The Goodyear Tire & Rubber Company (US) 2013-06-26 EP claimed
US-20130153101-A1 TRUCK TIRE WITH RUBBER TREAD GOODYEAR TIRE & RUBBER COMPANY, THE 2013-06-20 US claimed
WO-2012146759-A1 METHOD FOR PRODUCING RUBBER MIXTURES LANXESS DEUTSCHLAND GMBH (DE) 2012-11-01 WO claimed
EP-2517899-A1 Method for manufacturing rubber mixtures Lanxess Deutschland GmbH (DE) 2012-10-31 EP claimed
US-20110105669-A1 PROCESS OF FORMING VULCANIZABLE ELASTOMERIC COMPOSITIONS USING ULTRA ACCELERATORS AND PRODUCTS FORMED THEREFROM FLEXSYS AMERICA L.P. (US) 2011-05-05 US claimed
EP-2001952-B1 BONDING AGENTS AND SEALANTS BASED ON LIQUID RUBBERS HENKEL AG & CO KGAA (DE) 2009-11-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239990-A1 ORGANOSILYL POLYSULFIDES, AND RUBBER MIXTURES CONTAINING SAME TYRO3, WEE1, TYK2 MGLL 2416/4885ALDH1A1 4243/4885HDAC3 2548/4885
US-20240294557-A1 ORGANOSILYL POLYSULFIDES, AND RUBBER MIXTURES CONTAINING SAME SRSF1, WEE1, STS MGLL 2161/4885ALDH1A1 4294/4885HDAC3 2400/4885
US-20240270939-A1 ORGANOSILYL POLYSULFIDES AND RUBBER MIXTURES CONTAINING SAME SRSF1, WEE1, STS MGLL 2219/4885ALDH1A1 4192/4885HDAC3 2338/4885
US-20260055258-A1 A RUBBER COMPOUND MIXTURE SRM, SRMS, PRMT1 MGLL 3115/4885ALDH1A1 4675/4885HDAC3 1223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.