Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 7/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8132246 | 0.78 | CNR2 (0.43) | CDK1MAPKAPK2KDM4ENPC1ALDH1A1 | |
| SCHEMBL8118109 | 0.77 | MTNR1A (0.64) | MTNR1AMTNR1BKDM4EALDH1A1POLB | |
| SCHEMBL8133449 | 0.75 | NPC1 (0.42) | PLA2G2AKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL8133389 | 0.75 | MTNR1A (0.62) | MTNR1AMTNR1BPLA2G2AKDM4ENPC1 | |
| SCHEMBL8127298 | 0.74 | L3MBTL1 (0.40) | MTNR1AMTNR1BCDK1MAPKAPK2KDM4E | |
| SCHEMBL8132743 | 0.73 | RAB9A (0.37) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL8131878 | 0.71 | CLK1 (0.41) | MTNR1AMTNR1BKDM4ENPC1ALDH1A1 | |
| SCHEMBL8117069 | 0.70 | NR1D1 (0.43) | MTNR1AMTNR1BKDM4EMAPTRAB9A | |
| SCHEMBL8118630 | 0.70 | ATM (0.46) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL4450287 | 0.65 | ACHE (0.43) | MTNR1AMTNR1BNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147110-A | MELATONINERGIC AGENTS; SLEEP, EATING, CENTRAL NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-14 | — | — | US | disclosed |
| EP-0926145-A1 | Napthalene compounds, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-30 | — | — | EP | disclosed |