Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126477 | 0.89 | GRIA1 (0.38) | PTGS2CA1CA2CA9CA12 | |
| SCHEMBL8126480 | 0.89 | GRIA1 (0.38) | PTGS2CA1CA2CA9CA12 | |
| SCHEMBL4370479 | 0.88 | HTR6 (0.47) | GRIA1GRIA2GRIA3GRIA4HTR6 | |
| SCHEMBL6609340 | 0.86 | CASP3 (0.47) | HTR6BRD4 | |
| SCHEMBL8134987 | 0.85 | SMN1; SMN2 (0.42) | GRIA1GRIA2GRIA3GRIA4HTR6 | |
| SCHEMBL13592440 | 0.85 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8102934 | 0.85 | CES1 (0.39) | GRIA1GRIA2GRIA3GRIA4HTR6 | |
| SCHEMBL6609831 | 0.85 | MCHR1 (0.39) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6607897 | 0.85 | CYP2C9 (0.39) | GRIA1GRIA2GRIA3GRIA4HTR6 | |
| SCHEMBL8136178 | 0.84 | MEN1 (0.36) | GRIA1GRIA2GRIA3GRIA4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781285-B1 | FUSED INDOLE AND QUINOXALINE DERIVATIVES, THEIR PREPARATION AND USE AS GLUTAMATE ANTAGONISTS | NEUROSEARCH AS (DK) | 2000-01-12 | — | — | EP | disclosed |
| US-5801174-A | CEREBROVASCULAR DISORDERS | NEUROSEARCH A/S (DK) | 1998-09-01 | — | — | US | disclosed |
| WO-1996008495-A1 | FUSED INDOLE AND QUINOXALINE DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 1996-03-21 | — | — | WO | disclosed |