Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | YAP1 | P46937 | 1/20 | 0.30 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446501 | 0.84 | SNCA (0.36) | TDP1ALDH1A1POLBLMNAGAA | |
| SCHEMBL21358780 | 0.82 | TYR (0.41) | TDP1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL10596213 | 0.80 | ALDH1A1 (0.41) | TDP1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL10598218 | 0.77 | SNCA (0.39) | TDP1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL729517 | 0.76 | POLB (0.57) | TDP1ALDH1A1POLBLMNAGAA | |
| SCHEMBL9277018 | 0.76 | LMNA (0.47) | ALDH1A1POLBLMNAMAPTHTT | |
| SCHEMBL1804750 | 0.76 | SNCA (0.38) | TDP1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL1727437 | 0.76 | SNCA (0.38) | TDP1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL3339141 | 0.76 | FFAR4 (0.40) | TDP1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL16684874 | 0.75 | LMNA (0.43) | ALDH1A1POLBLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1029854-A1 | Oxazolidinones and their use as antibacterial agents | BAYER AG (DE) | 2000-08-23 | — | — | EP | disclosed |