Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21358780 | 0.89 | TYR (0.41) | SNCAALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL10596213 | 0.86 | ALDH1A1 (0.41) | SNCAALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL9277018 | 0.85 | LMNA (0.47) | SNCAALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8134017 | 0.84 | TDP1 (0.39) | SNCAALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL16684874 | 0.84 | LMNA (0.43) | ALDH1A1TSHRSMN1; SMN2LMNAMAPT | |
| SCHEMBL10598218 | 0.83 | SNCA (0.39) | SNCAALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL1804750 | 0.81 | SNCA (0.38) | SNCAALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL3339141 | 0.81 | FFAR4 (0.40) | SNCAALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL1727437 | 0.81 | SNCA (0.38) | SNCAALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL2337810 | 0.80 | ALDH1A1 (0.38) | SNCAALDH1A1HSD17B10TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942907-A1 | 2R, 4S, S, R- AND 2S, 4R, S, R-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1999-09-22 | — | — | EP | claimed |
| EP-0938487-A2 | 2$i(R),4$i(S),$i(R),$i(S)- AND 2$i(S),4$i(R),$i(R),$i(S)-HYDROXYITRACONAZOLE- AND HYDROXYSAPERCONAZOLE DERIVATIVES | SEPRACOR, INC. (US) | 1999-09-01 | — | — | EP | claimed |
| EP-0938484-A1 | 2R,4S,R,R- AND 2S,4R,R,R-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1999-09-01 | — | — | EP | claimed |
| EP-0937071-A1 | 2R,4S,S,S- AND 2S,4R,S,S-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1999-08-25 | — | — | EP | claimed |
| WO-1998021213-A2 | 2R,4S,R,S- AND 2S,4R,R,S-HYDROXYITRACONAZOLE- AND HYDROXYSAPERCONAZOLE DERIVATIVES | SEPRACOR, INC. (US) | 1998-05-22 | — | — | WO | claimed |
| WO-1998021205-A1 | 2R,4S,R,R- AND 2S,4R,R,R-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1998-05-22 | — | — | WO | claimed |
| WO-1998021204-A1 | 2R,4S,S,S- AND 2S,4R,S,S-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1998-05-22 | — | — | WO | claimed |
| WO-1998021203-A1 | 2R,4S,S,R- AND 2S,4R,S,R-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1998-05-22 | — | — | WO | claimed |
| EP-0938487-A2 | 2$i(R),4$i(S),$i(R),$i(S)- AND 2$i(S),4$i(R),$i(R),$i(S)-HYDROXYITRACONAZOLE- AND HYDROXYSAPERCONAZOLE DERIVATIVES | SEPRACOR, INC. (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998021213-A2 | 2R,4S,R,S- AND 2S,4R,R,S-HYDROXYITRACONAZOLE- AND HYDROXYSAPERCONAZOLE DERIVATIVES | SEPRACOR, INC. (US) | 1998-05-22 | — | — | WO | disclosed |
| US-5174927-A | Detergent and builders | THE PROCTER & GAMBLE COMPANY (US) | 1992-12-29 | — | — | US | disclosed |