Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8134540 | 0.86 | ALDH1A1 (0.50) | KDM4EPOLBCYP2D6BLMCHRM2 | |
| SCHEMBL2443032 | 0.82 | CHRM2 (0.54) | KDM4EPOLBCYP2D6BLMCHRM2 | |
| Hydrochloric Acid SCHEMBL4541197 | 0.81 | CHRM2 (0.52) | KDM4EPOLBCYP2D6BLMCHRM2 | |
| Dimenoxadol SCHEMBL25993 | 0.77 | CYP3A4 (0.68) | KDM4EPOLBCYP2D6BLMCHRM2 | |
| SCHEMBL9623042 | 0.77 | TSHR (0.47) | KDM4EPOLBCYP2D6CHRM2OPRM1 | |
| SCHEMBL11295018 | 0.76 | CES1 (0.57) | KDM4EPOLBCYP2D6BLMCHRM2 | |
| Dimenoxadol SCHEMBL2886211 | 0.76 | CYP3A4 (0.70) | KDM4EPOLBCYP2D6BLMCHRM2 | |
| Dimenoxadol SCHEMBL79044 | 0.76 | CYP3A4 (0.70) | KDM4EPOLBCYP2D6BLMCHRM2 | |
| SCHEMBL28598274 | 0.75 | TSHR (0.49) | KDM4EPOLBCYP2D6CHRM2OPRM1 | |
| Moxastine SCHEMBL29281 | 0.75 | CHRM2 (0.71) | KDM4EPOLBCYP2D6BLMCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069149-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | TERUMO KABUSHIKI KAISHA (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0894797-A1 | NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1999-02-03 | — | — | EP | disclosed |