Moxastine

Moxastine

SCHEMBL29281

CN(C)CCOC(C)(c1ccccc1)c1ccccc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.71
CYP2D6 P10635 3/20 0.59
BLM P54132 1/20 0.59
KDM4E B2RXH2 4/20 0.49
POLB P06746 1/20 0.49
OPRM1 P35372 4/20 0.46
DRD3 P35462 4/20 0.46
LMNA P02545 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ADRA2A P08913 2/20 0.46
CHRM1 P11229 2/20 0.46
SLC6A2 P23975 2/20 0.46
SLC6A4 P31645 2/20 0.46
ADRA1A P35348 2/20 0.46
SLC6A3 Q01959 2/20 0.46
KCNH2 Q12809 2/20 0.46
CYP1A2 P05177 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM5 P08912 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorphenoxamine SCHEMBL29208 0.90 CHRM2 (0.61) CHRM2CYP2D6BLMKDM4EPOLB
Embramine SCHEMBL28365 0.90 CHRM2 (0.61) CHRM2CYP2D6BLMKDM4EPOLB
Chlorphenoxamine SCHEMBL125112 0.89 CHRM2 (0.59) CHRM2CYP2D6BLMKDM4EPOLB
Embramine SCHEMBL1650532 0.89 CHRM2 (0.59) CHRM2CYP2D6BLMKDM4EPOLB
Chlorphenoxamine SCHEMBL1649036 0.87 CHRM2 (0.62) CHRM2CYP2D6BLMKDM4EPOLB
Doxylamine SCHEMBL12959067 0.84 CHRM2 (1.00) CHRM2CYP2D6BLMKDM4EPOLB
Doxylamine SCHEMBL30116312 0.84 CHRM2 (1.00) CHRM2CYP2D6BLMKDM4EPOLB
Doxylamine SCHEMBL4709 0.84 CHRM2 (1.00) CHRM2CYP2D6BLMKDM4EPOLB
Doxylamine SCHEMBL30702275 0.84 CHRM2 (1.00) CHRM2CYP2D6BLMKDM4EPOLB
Doxylamine SCHEMBL17047020 0.83 CHRM2 (0.97) CHRM2CYP2D6BLMKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
WO-2014186623-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF A CHAGAS DISEASE BIOMED VALLEY DISCOVERIES (US) 2014-11-20 WO claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20050282879-A1 Methods and composition for treatment of migraine and symptoms thereof SALEHANI FOAD 2005-12-22 US claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-12403094-B2 Rheological solid oral composition THE PROCTER & GAMBLE COMPANY (US) 2025-09-02 US disclosed
US-12372536-B2 Tumor necrosis factor-like ligand 1A specific antibodies and compositions and uses thereof PFIZER INC. (US) 2025-07-29 US disclosed
US-20250032643-A1 SYNTHETIC RECEPTORS UCL BUSINESS LTD (GB) 2025-01-30 US disclosed
US-20240425441-A9 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY ICOSA PHARMA INC. (CA) 2024-12-26 US disclosed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO disclosed
WO-1999025328-A1 (+)-EPHEDRINE AS A SYMPATHOMIMETIC DRUG WARNER-LAMBERT COMPANY (US) 1999-05-27 WO disclosed
EP-0910410-A1 TOPICAL COMPOSITION COMPRISING A COMBINATION OF ANTIHISTAMINIC COMPOUNDS WITH TERPENOID COMPOUNDS Novartis Consumer Health S.A. (CH) 1999-04-28 EP disclosed
WO-1998001134-A1 ORAL PHARMACEUTICAL COMBINATIONS OF ANTIHISTAMINIC COMPOUNDS AND TERPENOIDS NOVARTIS CONSUMER HEALTH S.A. (CH) 1998-01-15 WO disclosed
WO-1998000168-A1 TOPICAL COMPOSITION COMPRISING A COMBINATION OF ANTIHISTAMINIC COMPOUNDS WITH TERPENOID COMPOUNDS NOVARTIS CONSUMER HEALTH S.A. (CH) 1998-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282879-A1 Methods and composition for treatment of migraine and symptoms thereof HRH3, HRH4, HNMT CHRM2 145/4885CYP2D6 785/4885BLM 1779/4885
US-20240425441-A9 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY ALOX12, ALOX15B, ALOX5 CHRM2 1478/4885CYP2D6 312/4885BLM 3103/4885
US-20250032643-A1 SYNTHETIC RECEPTORS GRM5, GRM3, GRM1 CHRM2 241/4885CYP2D6 3455/4885BLM 4318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.