Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 18/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875008 | 0.86 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6THRATHRB | |
| SCHEMBL8136112 | 0.82 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6S1PR1THRA | |
| SCHEMBL8876220 | 0.80 | HDAC6 (0.46) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8136126 | 0.80 | PRSS1 (0.49) | THRATHRB | |
| SCHEMBL23588051 | 0.79 | THRA (0.52) | S1PR1THRATHRB | |
| SCHEMBL19411800 | 0.77 | THRA (0.58) | S1PR1THRATHRB | |
| SCHEMBL13139482 | 0.77 | THRA (0.58) | S1PR1THRATHRB | |
| SCHEMBL8136926 | 0.77 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6S1PR1 | |
| SCHEMBL10507968 | 0.76 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6S1PR1THRA | |
| SCHEMBL8875413 | 0.76 | NR1I2 (0.47) | NR1I2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566199-B1 | 1,2,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | SANOFI SA (FR) | 2000-03-01 | — | — | EP | disclosed |
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5349068-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0566199-A1 | 1,2,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use a s antiviral agents | STERLING WINTHROP INC. (US) | 1993-10-20 | — | — | EP | disclosed |