Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875008 | 0.84 | NR1I2 (0.41) | PRSS1THRATHRBKMT2AMEN1 | |
| SCHEMBL8136130 | 0.82 | PRSS1 (0.49) | PRSS1POLBTHRATHRBKMT2A | |
| SCHEMBL8136108 | 0.80 | NR1I2 (0.45) | THRATHRB | |
| SCHEMBL8876220 | 0.79 | HDAC6 (0.46) | PRSS1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8121009 | 0.78 | MAPT (0.45) | PRSS1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11031527 | 0.76 | ALDH1A1 (0.48) | PRSS1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8138666 | 0.74 | NR1I2 (0.54) | THRATHRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL8130660 | 0.74 | CYP3A4 (0.43) | PRSS1POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL8135973 | 0.74 | NR1I2 (0.61) | POLBKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL8875258 | 0.73 | NR1I2 (0.44) | KMT2AMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566199-B1 | 1,2,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | SANOFI SA (FR) | 2000-03-01 | — | — | EP | disclosed |
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5349068-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0566199-A1 | 1,2,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use a s antiviral agents | STERLING WINTHROP INC. (US) | 1993-10-20 | — | — | EP | disclosed |