Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6619396 | 0.99 | ALDH1A1 (0.43) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL6618725 | 0.91 | P2RX7 (0.42) | ALDH1A1DRD3DRD2ALOX5P2RX7 | |
| SCHEMBL7009681 | 0.90 | ALDH1A1 (0.46) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6617880 | 0.90 | ALOX5 (0.46) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL6622834 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL6621990 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6620536 | 0.81 | ALOX5 (0.48) | ALDH1A1MEN1KMT2ATDP1ALOX5 | |
| Hydrochloric Acid SCHEMBL6619934 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL7219268 | 0.79 | P2RX7 (0.48) | ALOX5P2RX7 | |
| SCHEMBL6620940 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNAGAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979231-A1 | CONDENSED PYRIDAZINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998049167-A1 | CONDENSED PYRIDAZINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |