Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133198 | 0.81 | NPSR1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10MAOB | |
| SCHEMBL8405209 | 0.81 | MAOB (0.36) | ALDH1A1KDM4EHPGDHSD17B10MAOB | |
| SCHEMBL8135015 | 0.79 | NPSR1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10MAOB | |
| SCHEMBL8134482 | 0.77 | FUCA1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10MAOB | |
| SCHEMBL6732023 | 0.74 | BAZ2B (0.38) | ALDH1A1KDM4EHPGDHSD17B10MAOB | |
| SCHEMBL8549368 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL19973511 | 0.68 | TSHR (0.49) | ALDH1A1KDM4EHPGDHSD17B10MAOB | |
| SCHEMBL6732015 | 0.68 | BAZ2B (0.41) | ALDH1A1KDM4EHSD17B10MAOBMAPT | |
| SCHEMBL19973995 | 0.65 | MAPT (0.45) | ALDH1A1HPGDMAPTLMNAKMT2A | |
| SCHEMBL8549364 | 0.65 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159904-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0970956-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |