Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135012 | 0.87 | BRD4 (0.41) | KDM4ELMNAALDH1A1MAPTNPC1 | |
| SCHEMBL8549364 | 0.85 | ALDH1A1 (0.37) | KDM4ELMNAALDH1A1MAPTNPC1 | |
| SCHEMBL8128418 | 0.83 | KDM4E (0.33) | KDM4EALDH1A1MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL8133195 | 0.80 | LMNA (0.40) | BAZ2BBAZ2ACYP4F2CYP4A11KDM4E | |
| SCHEMBL8405207 | 0.78 | KDM4E (0.38) | BAZ2BBAZ2ACYP4F2CYP4A11KDM4E | |
| SCHEMBL8136836 | 0.78 | BAZ2B (0.40) | BAZ2BBAZ2ACYP4F2CYP4A11KDM4E | |
| SCHEMBL8544578 | 0.75 | KDM4E (0.40) | BAZ2BBAZ2ACYP4F2CYP4A11KDM4E | |
| SCHEMBL8544581 | 0.75 | KDM4E (0.40) | BAZ2BBAZ2ACYP4F2CYP4A11KDM4E | |
| SCHEMBL7132465 | 0.75 | TSHR (0.41) | KDM4ELMNAALDH1A1MAPTNPC1 | |
| SCHEMBL8135395 | 0.74 | BAZ2B (0.40) | BAZ2BBAZ2ACYP4F2CYP4A11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677460-B1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030236421-A1 | AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2003-12-25 | — | — | US | disclosed |
| EP-1044973-B1 | Process for the dehalogenation of thiochroman and dihydrobenzothiophene derivatives | AMERICAN CYANAMID CO (US) | 2003-10-08 | — | — | EP | disclosed |
| US-20020133024-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2002-09-19 | — | — | US | disclosed |
| US-20010051733-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2001-12-13 | — | — | US | disclosed |
| US-6180797-B1 | MULTISTAGE REACTION AND HYDROLYSIS TO FORM HERBICIDES | AMERICAN CYANAMID CO. | 2001-01-30 | — | — | US | disclosed |
| US-6159904-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| US-6136755-A | HERBICIDES | IDEMITSU KOSAN CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1044973-A2 | Process for the dehalogenation of thiochroman and dihydrobenzothiophene derivatives | American Cyanamid Company (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-2000059898-A2 | PROCESS FOR THE DEHALOGENATION OF THIOCHROMAN AND DIHYDROBENZOTHIOPHENE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |
| US-6103668-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-08-15 | — | — | US | disclosed |
| US-6063936-A | CARBOXY SUBSTITUTED BENZOTHIOPHENES USED AS HERBICIDE | IDEMITSU KOSAN CO., LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| EP-0970956-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5767289-A | HERBICIDE INTERMEDIATES | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0810226-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |
| US-5607898-A | HERBICIDES | IDEMITSU KOSAN COMPANY, LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236421-A1 | AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS | XDH, SULT2A1, NAT1 | BAZ2B 1721/4885BAZ2A 1924/4885CYP4F2 368/4885 |
| US-20010051733-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | XDH, SULT2A1, NAT1 | BAZ2B 1721/4885BAZ2A 1924/4885CYP4F2 368/4885 |
| US-20020133024-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | XDH, SULT2A1, NAT1 | BAZ2B 1721/4885BAZ2A 1924/4885CYP4F2 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.