Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135015 | 0.88 | NPSR1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL6732023 | 0.87 | BAZ2B (0.38) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL8136281 | 0.83 | PARP1 (0.35) | ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL8133198 | 0.77 | NPSR1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL8135092 | 0.74 | ALDH1A1 (0.30) | ALDH1A1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8405209 | 0.74 | MAOB (0.36) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL8137342 | 0.72 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL8122612 | 0.70 | MEN1 (0.33) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL8128422 | 0.69 | FABP4 (0.34) | HPGDHSD17B10MAPTLMNATSHR | |
| SCHEMBL8126793 | 0.69 | MAPT (0.32) | ALDH1A1HPGDKMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818455-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-01-14 | — | — | EP | disclosed |