Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.31 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNK18 | Q7Z418 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL815039 | 1.00 | CES1 (0.42) | CES1PARP1TSHRBCL2L1BAD | |
| SCHEMBL813996 | 1.00 | CES1 (0.42) | CES1PARP1TSHRBCL2L1BAD | |
| SCHEMBL814015 | 1.00 | CES1 (0.42) | CES1PARP1TSHRBCL2L1BAD | |
| SCHEMBL816141 | 1.00 | CES1 (0.42) | CES1PARP1TSHRBCL2L1BAD | |
| SCHEMBL822204 | 1.00 | CES1 (0.42) | CES1PARP1TSHRBCL2L1BAD | |
| SCHEMBL814983 | 1.00 | CES1 (0.42) | CES1PARP1TSHRBCL2L1BAD | |
| SCHEMBL814798 | 1.00 | CES1 (0.42) | CES1PARP1TSHRBCL2L1BAD | |
| SCHEMBL817177 | 0.98 | CES1 (0.44) | CES1PARP1TSHRBCL2L1BAD | |
| SCHEMBL816475 | 0.95 | PARP1 (0.41) | CES1PARP1TSHRBCL2L1BAD | |
| SCHEMBL953470 | 0.81 | CES1 (0.53) | CES1PARP1TSHRBCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539993-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| EP-3022233-B1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-20180066083-A1 | Cyclopropyl Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-03-08 | — | — | US | disclosed |
| US-9834628-B2 | Cyclopropyl substituted metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-12-05 | — | — | US | disclosed |
| EP-1960411-B1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2016-08-31 | — | — | EP | disclosed |
| EP-3022233-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| US-9163046-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-10-20 | — | — | US | disclosed |
| WO-2015009473-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| US-20150025207-A1 | Cyclopropyl Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20070135595-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS, INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135594-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20060183874-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-08-17 | — | — | US | disclosed |
| US-20060160968-A1 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-07-20 | — | — | US | disclosed |
| US-20060160967-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-07-20 | — | — | US | disclosed |
| WO-2006065844-A2 | PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-06-22 | — | — | WO | disclosed |
| WO-2006065843-A2 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-06-22 | — | — | WO | disclosed |
| WO-2006065906-A2 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | OPRM1, POLM, AP1M1 | CES1 4170/4885PARP1 106/4885TSHR 1993/4885 |
| US-20060183874-A1 | Halogen substituted metallocene compounds for olefin polymerization | B2M, CDYL, MLX | CES1 4417/4885PARP1 2479/4885TSHR 2843/4885 |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | SP1, TTL, TTLL12 | CES1 1918/4885PARP1 4458/4885TSHR 47/4885 |
| US-20070135594-A1 | Halogen substituted metallocene compounds for olefin polymerization | MLX, AP1M1, AP2M1 | CES1 4576/4885PARP1 490/4885TSHR 2259/4885 |
| US-20070135595-A1 | Halogen substituted metallocene compounds for olefin polymerization | AP2M1, AP1M1, CPNE4 | CES1 4295/4885PARP1 807/4885TSHR 1486/4885 |
| US-20180066083-A1 | Cyclopropyl Substituted Metallocene Catalysts | CPNE4, TIMM13, NECTIN4 | CES1 2865/4885PARP1 157/4885TSHR 4546/4885 |
| US-20060160967-A1 | Halogen substituted metallocene compounds for olefin polymerization | OR10J3, ZRANB2, SLC39A3 | CES1 4775/4885PARP1 611/4885TSHR 1942/4885 |
| US-20060160968-A1 | Process for producing substituted metallocene compounds for olefin polymerization | OSBP, OSBPL3, OSBP2 | CES1 2580/4885PARP1 1272/4885TSHR 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.