Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130885 | 0.84 | KDM4E (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL24009065 | 0.78 | ALDH1A1 (0.43) | ALDH1A1ADORA2BKDM4EL3MBTL1GAA | |
| SCHEMBL11244456 | 0.75 | MEN1 (0.68) | KDM4EHTTMEN1KMT2AMAPT | |
| SCHEMBL24009064 | 0.74 | ALDH1A1 (0.58) | ALDH1A1ADORA2BKDM4EL3MBTL1MAPK1 | |
| SCHEMBL24612894 | 0.73 | KDM4E (0.49) | ALDH1A1ADORA2BKDM4EL3MBTL1MAPK1 | |
| SCHEMBL8803058 | 0.73 | KDM4E (0.56) | ALDH1A1ADORA2BKDM4EL3MBTL1MAPK1 | |
| SCHEMBL3785688 | 0.70 | ALDH1A1 (0.52) | ALDH1A1KDM4EL3MBTL1GAAMEN1 | |
| SCHEMBL24393211 | 0.69 | ADORA2B (0.57) | ALDH1A1ADORA2BKDM4EL3MBTL1MAPK1 | |
| SCHEMBL29091657 | 0.69 | ALDH1A1 (0.51) | ALDH1A1ADORA2BKDM4EL3MBTL1MAPK1 | |
| SCHEMBL3818341 | 0.68 | ALDH1A1 (0.54) | ALDH1A1KDM4EL3MBTL1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009748-A1 | 3-ALKYLPYRROLO 3,2-$i(c)]QUINOLINE DERIVATIVES | Korea Research Institute of Chemical Technology (KR) | 2000-06-21 | — | — | EP | disclosed |
| WO-2000001696-A1 | 3-ALKYLPYRROLO[3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2000-01-13 | — | — | WO | disclosed |