Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ATP4A | P20648 | 1/20 | 0.42 |
| ▸ | ATP4B | P51164 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138356 | 0.84 | ALDH1A1 (0.46) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL24008926 | 0.81 | KDM4E (0.48) | KDM4EHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9685903 | 0.78 | KDM4E (0.46) | KDM4EHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL29254511 | 0.77 | KDM4E (0.48) | KDM4EHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6381401 | 0.77 | HPGDS (0.54) | KDM4EHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL28926222 | 0.76 | PIN1 (0.53) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8537645 | 0.76 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL9652279 | 0.76 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL1257667 | 0.76 | MEN1 (0.51) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8537647 | 0.75 | MEN1 (0.50) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009748-A1 | 3-ALKYLPYRROLO 3,2-$i(c)]QUINOLINE DERIVATIVES | Korea Research Institute of Chemical Technology (KR) | 2000-06-21 | — | — | EP | disclosed |
| WO-2000001696-A1 | 3-ALKYLPYRROLO[3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2000-01-13 | — | — | WO | disclosed |