Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536612 | 0.91 | CHRM2 (0.42) | KMT2AMEN1BLMCHRM2CHRM4 | |
| SCHEMBL8132057 | 0.83 | KDM4E (0.52) | ALDH1A1SMN1; SMN2TSHRHSD17B10KDM4E | |
| SCHEMBL9535563 | 0.81 | TP53 (0.51) | ALDH1A1SMN1; SMN2L3MBTL1CHRM1GAA | |
| SCHEMBL9535375 | 0.81 | HRH1 (0.55) | ALDH1A1SMN1; SMN2TSHRHSD17B10KDM4E | |
| SCHEMBL8566268 | 0.79 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TSHRHSD17B10KDM4E | |
| SCHEMBL9538121 | 0.70 | KDM4E (0.42) | ALDH1A1SMN1; SMN2TSHRHSD17B10KDM4E | |
| SCHEMBL9699749 | 0.70 | KDM4E (0.51) | ALDH1A1SMN1; SMN2TSHRHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL9537163 | 0.70 | KDM4E (0.42) | ALDH1A1SMN1; SMN2TSHRHSD17B10KDM4E | |
| SCHEMBL11022779 | 0.69 | KMT2A (0.56) | ALDH1A1SMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL7629465 | 0.69 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539420-B1 | SUBSTITUTED THIAZOLYL AND SUBSTITUTED PYRIDINYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1992001697-A1 | NOVEL SUBSTITUTED THIAZOLYL AND SUBSTITUTED PYRIDINYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-06 | — | — | WO | disclosed |