Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233486 | 0.78 | MAPT (0.45) | ALDH1A1MAPTRECQLCASP3KMT2A | |
| SCHEMBL1232705 | 0.78 | KMT2A (0.48) | ALDH1A1MAPTRECQLCASP3KMT2A | |
| SCHEMBL21550218 | 0.74 | HTT (0.43) | ALDH1A1HTTMAPTRECQLKDM4E | |
| SCHEMBL1233755 | 0.73 | GABRP (0.45) | ALDH1A1HTTMAPTCYP1A2CYP3A4 | |
| SCHEMBL588771 | 0.70 | MAPT (0.51) | ALDH1A1HTTMAPTRECQLCASP3 | |
| SCHEMBL16881138 | 0.70 | MAPK8 (0.43) | ALDH1A1HTTMAPTKMT2AMEN1 | |
| SCHEMBL18489369 | 0.69 | MAPT (0.54) | ALDH1A1HTTMAPTRECQLCASP3 | |
| SCHEMBL18489387 | 0.69 | CASP3 (0.50) | ALDH1A1HTTMAPTRECQLCASP3 | |
| SCHEMBL12486332 | 0.68 | PABPC1 (0.51) | ALDH1A1MAPTRECQLCASP3KMT2A | |
| SCHEMBL3720990 | 0.68 | ALDH1A1 (0.51) | ALDH1A1HTTMAPTRECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020447-A1 | PYRAZOLE COMPOUNDS AND PLANT DISEASE CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |