SCHEMBL814080

SCHEMBL814080

CC(C)(C)c1ccc2c(c1)-c1cc(C(C)(C)C)ccc1[N]2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
NPC1 O15118 1/20 0.45
PLA2G1B P04054 1/20 0.45
NFKB1 P19838 1/20 0.45
CASP3 P42574 1/20 0.45
RAB9A P51151 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ATG4B Q9Y4P1 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21753754 0.90 ALDH1A1 (0.52) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL23629575 0.84 KIF11 (0.45) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL2961621 0.83 KIF11 (0.50) ALDH1A1NPC1RAB9AKMT2ATSHR
SCHEMBL16333367 0.81 ALDH1A1 (0.45) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL22118217 0.77 RXRB (0.45) ALDH1A1NPC1RAB9AMAPTGAA
SCHEMBL2689834 0.77 SHBG (0.47) ALDH1A1NPC1CASP3RAB9ASENP8
SCHEMBL3877841 0.76 KIF11 (0.43) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL1134715 0.74 ALDH1A1 (0.58) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL1134700 0.74 ALDH1A1 (0.58) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL14063515 0.72 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150502-A1 BIPHENYLPHENOL POLYMERIZATION CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-09 US claimed
CN-117659084-A Aromatic amine modified tridentate phosphine coordination copper complex, and preparation method and application thereof 黑龙江大学 2024-03-08 CN claimed
CN-114573507-B Thermal activation delayed fluorescent material based on axial chiral ketone receptor and preparation method and application thereof 中国科学院大学 2024-01-23 CN claimed
CN-116724062-A Biphenol polymerization catalyst 陶氏环球技术有限责任公司 2023-09-08 CN claimed
CN-110809586-B Biaryl phenoxy group IV transition metal catalysts for olefin polymerization 陶氏环球技术有限责任公司 2023-06-27 CN claimed
CN-110678488-B Biaryl phenoxy group IV transition metal catalysts for olefin polymerization 陶氏环球技术有限责任公司 2023-06-27 CN claimed
US-20230098987-A1 GAS-PHASE BIPHENYLPHENOL POLYMERIZATION CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-03-30 US claimed
US-20220403060-A1 BIDENTATE BIARYLPHENOXY GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION WITH CHAIN TRANSFER AGENTS DOW GLOBAL TECHNOLOGIES LLC (US) 2022-12-22 US claimed
US-20220403061-A1 BIPHENYLPHENOL POLYMERIZATION CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2022-12-22 US claimed
CN-110799551-B Biarylphenoxy group IV transition metal catalysts for olefin polymerization 陶氏环球技术有限责任公司 2022-12-13 CN claimed
EP-3013871-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS Dow Global Technologies LLC (US) 2016-05-04 EP claimed
US-20160108156-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC 2016-04-21 US claimed
WO-2016014749-A1 BIS-BIPHENYLPHENOXY CATALYSTS FOR POLYMERIZATION OF LOW MOLECULAR WEIGHT ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-01-28 WO claimed
WO-2014210333-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-31 WO claimed
US-8450438-B2 High temperature polyethylene solution polymerization process DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-05-28 US claimed
EP-2492287-A2 High temperature polyethylene solution polymerization process Dow Global Technologies LLC (US) 2012-08-29 EP claimed
US-20120108770-A1 HIGH TEMPERATURE POLYETHYLENE SOLUTION POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES, INC. (US) 2012-05-03 US claimed
WO-2011146044-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO claimed
EP-2024401-A2 HIGH TEMPERATURE POLYETHYLENE SOLUTION POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-02-18 EP claimed
WO-2007136496-A2 HIGH TEMPERATURE POLYETHYLENE SOLUTION POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2007-11-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108770-A1 HIGH TEMPERATURE POLYETHYLENE SOLUTION POLYMERIZATION PROCESS PUF60, PCBP1, EEF1D ALDH1A1 4584/4885NPC1 2556/4885PLA2G1B 2830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.