Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2961621 | 0.91 | KIF11 (0.50) | KIF11NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL23629575 | 0.87 | KIF11 (0.45) | KIF11NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL21753754 | 0.86 | ALDH1A1 (0.52) | KIF11NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2967623 | 0.82 | MEN1 (0.47) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL3876013 | 0.81 | MEN1 (0.40) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL22118217 | 0.79 | RXRB (0.45) | KIF11NPC1RAB9AKMT2AS1PR1 | |
| SCHEMBL20553766 | 0.77 | ABL1 (0.50) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL814080 | 0.76 | ALDH1A1 (0.45) | KIF11NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL814578 | 0.76 | MEN1 (0.47) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL20553967 | 0.75 | ENPP3 (0.44) | NPC1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482490-B2 | Amine compound having fluorene group as framework, process for producing the amine compound, and use of the amine compound | TOSOH CORPORATION (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20080194878-A1 | Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound | TOSOH CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| US-7189877-B2 | Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSCH CORPORATION (JP) | 2007-03-13 | — | — | US | disclosed |
| EP-1752440-A1 | AMINE COMPOUND HAVING FLUORENE GROUP AS FRAMEWORK, PROCESS FOR PRODUCING THE AMINE COMPOUND, AND USE OF THE AMINE COMPOUND | Tosoh Corporation (JP) | 2007-02-14 | — | — | EP | disclosed |
| EP-1400578-B1 | Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives | TOSOH CORP (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSOH CORPORATION | 2004-06-10 | — | — | US | disclosed |
| EP-1400578-A1 | Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives | Tosoh Corporation (JP) | 2004-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | AHR, NAT1, AR | KIF11 3501/4885NPC1 2320/4885RAB9A 1907/4885 |
| US-20080194878-A1 | Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound | TAAR1, SLC18A1, ADRB2 | KIF11 2692/4885NPC1 1532/4885RAB9A 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.