Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ASPH | Q12797 | 2/20 | 0.45 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567497 | 0.86 | ALDH1A1 (0.42) | KDM4EASPHKDM8ALDH1A1CYP3A4 | |
| SCHEMBL8563829 | 0.85 | MAPK1 (0.37) | KDM4EASPHKDM8TDP1ALDH1A1 | |
| SCHEMBL23022139 | 0.81 | KDM4E (0.43) | KDM4EASPHKDM8TDP1ALDH1A1 | |
| SCHEMBL8563396 | 0.79 | CES2 (0.39) | KDM4EASPHKDM8ALDH1A1L3MBTL1 | |
| SCHEMBL8564862 | 0.79 | KDM4E (0.37) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL8567191 | 0.77 | NAPRT (0.50) | KDM4EASPHKDM8TDP1ALDH1A1 | |
| SCHEMBL3709618 | 0.77 | GAA (0.39) | KDM4ETDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL8561698 | 0.76 | NSD2 (0.50) | CYP3A4L3MBTL1MEN1KMT2AMAPK8 | |
| SCHEMBL8560654 | 0.76 | RAB9A (0.52) | TDP1ALDH1A1CYP3A4L3MBTL1MAPT | |
| SCHEMBL8141010 | 0.76 | HTT (0.37) | TDP1ALDH1A1CYP3A4ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |