Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589997 | 0.74 | ALDH1A1 (0.41) | KDM4EPOLBTDP1MEN1HTT | |
| SCHEMBL1905689 | 0.71 | ALDH1A1 (0.39) | TSHRHTTRAB9A | |
| SCHEMBL329284 | 0.69 | — | — | |
| Acrylic Acid SCHEMBL28248820 | 0.68 | LMNA (0.34) | KDM4E | |
| SCHEMBL1727030 | 0.68 | — | — | |
| SCHEMBL502541 | 0.67 | TXNRD1 (0.44) | KDM4ERAB9A | |
| SCHEMBL29720239 | 0.67 | TXNRD1 (0.37) | — | |
| SCHEMBL11567573 | 0.67 | KDM4E (0.50) | KDM4EPOLBTDP1MEN1TSHR | |
| SCHEMBL28088968 | 0.66 | ALDH1A1 (0.34) | — | |
| Bromide SCHEMBL28322202 | 0.65 | TXNRD1 (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127548-A | PREPARING OPTIONALLY SUBSTITUED 3H-IMIDAZOLE-4-CARBALDEHYDE BY PROTECTING THE 3-AMINO GROUP, THEN FORMYLATING IN PRESENCE OF AN ORGANOMETALLIC COMPOUND AND ELECTROPHILE WITH FORMYL LEAVING GROUP, DEPROTECTING WITH ACID OR STRONG BASE | LONZA AG (CH) | 2000-10-03 | — | — | US | disclosed |