Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143057 | 0.87 | KMT2A (0.45) | LMNAALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL8144918 | 0.86 | NR1H4 (0.43) | LMNAALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL8003353 | 0.77 | HMGCR (0.47) | LMNAALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL8151087 | 0.74 | MEN1 (0.50) | ALDH1A1HTTMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL8144613 | 0.73 | MAPT (0.41) | LMNAALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL513250 | 0.72 | L3MBTL1 (0.56) | LMNAHTTMAPTL3MBTL1HPGD | |
| SCHEMBL513249 | 0.72 | L3MBTL1 (0.56) | LMNAHTTMAPTL3MBTL1HPGD | |
| SCHEMBL8437521 | 0.72 | L3MBTL1 (0.56) | LMNAHTTMAPTL3MBTL1HPGD | |
| SCHEMBL15162462 | 0.71 | ALDH1A1 (0.65) | LMNAALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL8150109 | 0.71 | MAPT (0.46) | LMNAALDH1A1HTTMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017918-A | Phenyl glycine compounds and methods of treating atherosclerosis and restenosis | WARNER-LAMBERT COMPANY (US) | 2000-01-25 | — | — | US | disclosed |