Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 13/20 | 1.00 |
| ▸ | MTNR1A | P48039 | 9/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143156 | 0.86 | MTNR1A (0.75) | MTNR1BMTNR1APGRNPC1TP53 | |
| SCHEMBL4720318 | 0.84 | MTNR1A (0.82) | MTNR1BMTNR1AMAPTNPC1TP53 | |
| SCHEMBL28212694 | 0.84 | MTNR1A (0.72) | MTNR1BMTNR1AMAPTNPC1TP53 | |
| SCHEMBL8324607 | 0.84 | MTNR1A (0.71) | MTNR1BMTNR1ANPC1RAB9A | |
| SCHEMBL23373385 | 0.82 | MTNR1B (0.69) | MTNR1BMTNR1APGR | |
| SCHEMBL4630369 | 0.81 | MTNR1B (1.00) | MTNR1BMTNR1APGRTP53 | |
| SCHEMBL8142314 | 0.81 | MTNR1B (1.00) | MTNR1BMTNR1APGR | |
| SCHEMBL8642683 | 0.81 | MTNR1A (0.71) | MTNR1BMTNR1ANPC1TP53RAB9A | |
| SCHEMBL13192697 | 0.80 | MTNR1A (0.66) | MTNR1BMTNR1A | |
| SCHEMBL15474281 | 0.80 | MTNR1A (0.66) | MTNR1BMTNR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090854-A | Aryloxyanilides and related compounds | BRISTOL-MEYERS COMPANY (US) | 2000-07-18 | — | — | US | disclosed |
| WO-1999048859-A1 | ARYLOXYANILIDES AND RELATED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-09-30 | — | — | WO | disclosed |