Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.75 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143122 | 0.86 | MTNR1B (1.00) | MTNR1AMTNR1BHSD17B10NPC1TP53 | |
| SCHEMBL28212694 | 0.81 | MTNR1A (0.72) | MTNR1AMTNR1BNPC1TP53PKM | |
| SCHEMBL883130 | 0.79 | TNKS (0.60) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL2436534 | 0.79 | L3MBTL1 (0.65) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL2189841 | 0.78 | NPC1 (0.47) | MTNR1AMTNR1BHSD17B10NPC1TP53 | |
| SCHEMBL521860 | 0.78 | AKR1C3 (0.68) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL8144897 | 0.78 | MTNR1B (0.75) | MTNR1AMTNR1BNPC1TP53PKM | |
| SCHEMBL13192697 | 0.77 | MTNR1A (0.66) | MTNR1AMTNR1B | |
| SCHEMBL14217726 | 0.77 | L3MBTL1 (0.56) | NPC1TP53RAB9ASMN1; SMN2PGR | |
| SCHEMBL16670220 | 0.76 | ALDH1A1 (0.77) | HSD17B10RAB9ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090854-A | Aryloxyanilides and related compounds | BRISTOL-MEYERS COMPANY (US) | 2000-07-18 | — | — | US | disclosed |