SCHEMBL81433

SCHEMBL81433

Cc1ccc(NC(N)=O)cc1

nearest known ligand 0.88

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.88
TDP1 Q9NUW8 1/20 0.64
PEPD P12955 1/20 0.64
NPC1 O15118 3/20 0.61
ALDH1A1 P00352 3/20 0.61
POLB P06746 1/20 0.61
KDM4E B2RXH2 1/20 0.61
DDAH1 O94760 1/20 0.60
RAB9A P51151 2/20 0.59
GAA P10253 1/20 0.57
MAPT P10636 1/20 0.57
GFER P55789 1/20 0.57
TGM2 P21980 1/20 0.55
MEN1 O00255 1/20 0.55
LMNA P02545 1/20 0.55
KMT2A Q03164 1/20 0.55
GLA P06280 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27918047 0.98 KIF11 (0.84) KIF11TDP1PEPDNPC1ALDH1A1
SCHEMBL27478177 0.98 KIF11 (0.84) KIF11TDP1PEPDNPC1ALDH1A1
SCHEMBL5428805 0.94 KIF11 (1.00) KIF11TDP1PEPDNPC1ALDH1A1
SCHEMBL11219391 0.88 KIF11 (0.70) KIF11TDP1PEPDNPC1ALDH1A1
SCHEMBL13750226 0.88 KIF11 (0.70) KIF11TDP1PEPDNPC1ALDH1A1
SCHEMBL5062623 0.87 PEPD (0.80) KIF11PEPDNPC1ALDH1A1RAB9A
SCHEMBL17189486 0.84 RAB9A (0.67) KIF11NPC1ALDH1A1POLBRAB9A
SCHEMBL12597618 0.82 KDM4E (0.68) KIF11TDP1NPC1ALDH1A1POLB
SCHEMBL11925383 0.81 SMN1; SMN2 (0.67) KIF11TDP1PEPDNPC1ALDH1A1
SCHEMBL455439 0.80 TDP1 (0.70) KIF11TDP1NPC1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 656 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431355-A Phenyl thiazole derivative, composition and application thereof 徐州医科大学 2025-02-14 CN claimed
CN-118530712-B Silicon-containing rubber fracturing fluid and preparation method thereof 广饶齐成新能源有限公司 2024-10-29 CN claimed
CN-113906321-B Polarizing plate, method for manufacturing same, and image display device 住友化学株式会社 2024-10-15 CN claimed
WO-2024176683-A1 SILICONE EMULSION COMPOSITION 信越化学工業株式会社 2024-08-29 WO claimed
CN-118530712-A Silicon-containing rubber fracturing fluid and preparation method thereof 广饶齐成新能源有限公司 2024-08-23 CN claimed
US-20240262801-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES MONDEGO BIO, LDA. (PT) 2024-08-08 US claimed
CN-117946033-A Preparation method for photo-promoted synthesis of urea compound 兰州大学 2024-04-30 CN claimed
CN-111601790-B Heteroaryl compounds as protein kinase inhibitors 福建海西新药创制股份有限公司 2023-03-31 CN claimed
CN-112250661-A Method for catalytically synthesizing lactide 南京大学 2021-01-22 CN claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
CN-1177343-A Cell adhesion inhibitors BIOGEN INC (US) 1998-03-25 CN claimed
US-5696110-A ANTIULCER AGENTS MERCK, SHARP & DOHME, LTD. (GB) 1997-12-09 US claimed
CN-1131509-A Sulphonylaminophenyluracil herbicides for paddy field BAYER AGROCHEM KK (JP) 1996-09-25 CN claimed
EP-0717403-A1 Heterocyclylazoaniline dyes, heterocyclylazoaniline dye metal complexes and their use in optical elements EASTMAN KODAK COMPANY (US) 1996-06-19 EP claimed
CN-1029582-C Herbicides for weed control in rice DU PONT (US) 1995-08-30 CN claimed
CN-1091133-A Cyclic amide compounds its preparation method and as weedicide ISHIHARA SANGYO KAISHA (JP) 1994-08-24 CN claimed
EP-0182166-B1 PROCESS FOR PREPARING PHENYLISOPROPYLUREA COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1989-05-31 EP claimed
CN-1031081-A The weedicide of control weeds in paddy field DU PONT (US) 1989-02-15 CN claimed
EP-0182166-A2 Process for preparing phenylisopropylurea compounds AMERICAN CYANAMID COMPANY (US) 1986-05-28 EP claimed
US-4578513-A Process for preparing phenylisopropylurea compounds AMERICAN CYANAMID COMPANY (US) 1986-03-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 KIF11 2646/4885TDP1 4027/4885PEPD 3259/4885
US-20240262801-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES PPM1A, TH, PPM1G KIF11 3848/4885TDP1 413/4885PEPD 648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.