SCHEMBL17189486

SCHEMBL17189486

Cc1ccc(NC(=O)Nc2cccc(NC(N)=O)c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.67
NPC1 O15118 4/20 0.67
KIF11 P52732 1/20 0.64
KDR P35968 1/20 0.59
SAE1 Q9UBE0 1/20 0.56
UBA2 Q9UBT2 1/20 0.56
CSF1R P07333 1/20 0.55
FLT1 P17948 1/20 0.55
FLT3 P36888 1/20 0.55
SMN1; SMN2 Q16637 3/20 0.54
TP53 P04637 2/20 0.54
KMT2A Q03164 2/20 0.54
ALDH1A1 P00352 1/20 0.54
PKM P14618 1/20 0.54
DDX3X O00571 2/20 0.53
PTPN7 P35236 1/20 0.53
MAPT P10636 2/20 0.53
POLB P06746 1/20 0.53
GBA1 P04062 1/20 0.53
MEN1 O00255 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12711075 0.91 RAB9A (0.77) RAB9ANPC1KDRSAE1UBA2
SCHEMBL17189470 0.86 SIRT1 (0.66) RAB9ANPC1KDRSMN1; SMN2TP53
SCHEMBL5852140 0.84 SAE1 (0.76) RAB9ANPC1KDRSAE1UBA2
SCHEMBL81433 0.84 KIF11 (0.88) RAB9ANPC1KIF11KMT2AALDH1A1
SCHEMBL14350754 0.83 DDX3X (0.77) RAB9ANPC1KDRSAE1UBA2
SCHEMBL27478177 0.82 KIF11 (0.84) RAB9ANPC1KIF11KMT2AALDH1A1
Hydrochloric Acid SCHEMBL27918047 0.82 KIF11 (0.84) RAB9ANPC1KIF11KMT2AALDH1A1
SCHEMBL3690365 0.82 MAPT (0.59) NPC1KIF11KMT2AALDH1A1DDX3X
SCHEMBL22588913 0.81 NPC1 (0.69) RAB9ANPC1KDRSAE1UBA2
SCHEMBL8885278 0.81 ALDH1A1 (0.52) SMN1; SMN2TP53KMT2AALDH1A1DDX3X

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933321-A1 GREASE COMPOSITION AMELIORATING LOW-TEMPERATURE FRETTING Kyodo Yushi Co., Ltd. (JP) 2015-10-21 EP disclosed