Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 7/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7727751 | 0.88 | CHRNB2 (0.45) | F2 | |
| SCHEMBL8144123 | 0.85 | MASP2 (0.34) | CTSCF2 | |
| SCHEMBL7722172 | 0.85 | MMP2 (0.40) | CTSCF2 | |
| SCHEMBL8149716 | 0.84 | F2 (0.33) | CTSCF2DPP4 | |
| Hydrochloric Acid SCHEMBL7729651 | 0.84 | MMP2 (0.40) | CTSCF2 | |
| SCHEMBL21436528 | 0.83 | PLA2G2A (0.39) | CTSCCNR2DPP8DPP9DPP7 | |
| SCHEMBL7727076 | 0.83 | PLA2G2A (0.39) | CTSCCNR2DPP8DPP9DPP7 | |
| SCHEMBL17770546 | 0.83 | POLB (0.41) | CTSCF2 | |
| Hydrochloric Acid SCHEMBL7729657 | 0.82 | POLB (0.40) | CTSCF2 | |
| SCHEMBL21436517 | 0.82 | F2 (0.36) | CTSCF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |