SCHEMBL814348

SCHEMBL814348

C=C1CCCC(C)(C)C1C(=O)OCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TRPA1 O75762 2/20 0.37
NR3C1 P04150 3/20 0.34
PGR P06401 3/20 0.34
AR P10275 3/20 0.34
NR3C2 P08235 1/20 0.34
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
PTPN2 P17706 1/20 0.32
PTPN1 P18031 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9798207 0.88 TRPA1 (0.36) ALDH1A1TRPA1NR3C1PGRAR
Ethyl Acetate SCHEMBL28147899 0.86 TRPA1 (0.38) ALDH1A1TRPA1NR3C1PGRAR
SCHEMBL3645946 0.84 ALDH1A1 (0.40) ALDH1A1TRPA1MEN1MAPTKMT2A
SCHEMBL9798347 0.84 GAA (0.37) ALDH1A1TRPA1NR3C1PGRAR
SCHEMBL14248383 0.83 ALDH1A1 (0.41) ALDH1A1LMNAMEN1MAPTKMT2A
SCHEMBL23530425 0.82 TRPA1 (0.39) ALDH1A1TRPA1NR3C1PGRAR
SCHEMBL755859 0.82 TRPA1 (0.39) ALDH1A1TRPA1NR3C1PGRAR
SCHEMBL29414123 0.82 TRPA1 (0.39) ALDH1A1TRPA1NR3C1PGRAR
SCHEMBL17129801 0.79 TRPA1 (0.38) TRPA1NR3C1PGRARNR3C2
SCHEMBL9798127 0.78 TRPA1 (0.37) TRPA1NR3C1PGRARNR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8067644-B2 Process for conducting an organic reaction in ionic liquids THE PROCTER & GAMBLE COMPANY (US) 2011-11-29 US claimed
EP-2370387-A2 PROCESS FOR CONDUCTING AN ORGANIC REACTION IN IONIC LIQUIDS The Procter & Gamble Company (US) 2011-10-05 EP claimed
WO-2010080505-A2 PROCESS FOR CONDUCTING AN ORGANIC REACTION IN IONIC LIQUIDS THE PROCTER & GAMBLE COMPANY (US) 2010-07-15 WO claimed
EP-0378825-B1 Alicyclic esters and their use as flavouring agents FIRMENICH & CIE (CH) 1994-07-06 EP claimed
US-5015625-A Methylenecyclohexane Carboxylates FIRMENICH SA (CH) 1991-05-14 US claimed
EP-2370387-A2 PROCESS FOR CONDUCTING AN ORGANIC REACTION IN IONIC LIQUIDS The Procter & Gamble Company (US) 2011-10-05 EP disclosed
WO-2010080505-A2 PROCESS FOR CONDUCTING AN ORGANIC REACTION IN IONIC LIQUIDS THE PROCTER & GAMBLE COMPANY (US) 2010-07-15 WO disclosed
US-5015625-A Methylenecyclohexane Carboxylates FIRMENICH SA (CH) 1991-05-14 US disclosed