SCHEMBL9798207

SCHEMBL9798207

C=C1CCCC(C)(C)C1C(=O)OCCC

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.36
PTPN1 P18031 2/20 0.33
PPM1B O75688 1/20 0.33
PPP1CC P36873 1/20 0.33
NR3C1 P04150 3/20 0.33
PGR P06401 3/20 0.33
AR P10275 3/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 1/20 0.33
NR3C2 P08235 1/20 0.33
ALDH1A1 P00352 3/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PTPN2 P17706 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL814348 0.88 ALDH1A1 (0.38) TRPA1PTPN1NR3C1PGRAR
SCHEMBL9798347 0.81 GAA (0.37) TRPA1PTPN1NR3C1PGRAR
SCHEMBL23530425 0.80 TRPA1 (0.39) TRPA1PTPN1NR3C1PGRAR
SCHEMBL755859 0.80 TRPA1 (0.39) TRPA1PTPN1NR3C1PGRAR
SCHEMBL29414123 0.80 TRPA1 (0.39) TRPA1PTPN1NR3C1PGRAR
Ethyl Acetate SCHEMBL28147899 0.78 TRPA1 (0.38) TRPA1NR3C1PGRARNR3C2
SCHEMBL9838357 0.78 LMNA (0.37) TRPA1PTPN1NR3C1PGRAR
SCHEMBL17129801 0.76 TRPA1 (0.38) TRPA1PTPN1NR3C1PGRAR
SCHEMBL9798127 0.76 TRPA1 (0.37) TRPA1PTPN1NR3C1PGRAR
SCHEMBL4359741 0.74 TRPA1 (0.41) TRPA1PTPN1NR3C1PGRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5015625-A Methylenecyclohexane Carboxylates FIRMENICH SA (CH) 1991-05-14 US disclosed