Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.35 |
| ▸ | PTGES | O14684 | 5/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157089 | 0.93 | APEX1 (0.36) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL8151217 | 0.83 | HTT (0.43) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL8152729 | 0.79 | POLB (0.43) | HTTPOLBAPEX1TDP1ALOX5 | |
| SCHEMBL8150966 | 0.79 | POLB (0.38) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL8157433 | 0.77 | APEX1 (0.39) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL8158569 | 0.76 | TDP1 (0.43) | HTTPOLBAPEX1TDP1ALDH1A1 | |
| SCHEMBL8144687 | 0.76 | ESR1 (0.41) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL8552120 | 0.76 | RAB9A (0.35) | HTTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8157309 | 0.75 | CA1 (0.40) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL8151145 | 0.75 | APEX1 (0.40) | HTTPOLBAPEX1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |