Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.34 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.34 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.34 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551274 | 0.82 | PLAAT3 (0.41) | RAB9ASMN1; SMN2NPC1PLAAT3PLAAT5 | |
| SCHEMBL8157089 | 0.78 | APEX1 (0.36) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8548079 | 0.78 | CA1 (0.41) | PLAAT3PLAAT5PLAAT2PLAAT4GAA | |
| SCHEMBL8547091 | 0.77 | GAA (0.39) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL8554560 | 0.77 | LY96 (0.48) | RAB9ASMN1; SMN2NPC1PLAAT3PLAAT5 | |
| SCHEMBL8552707 | 0.77 | ALDH1A1 (0.52) | RAB9ASMN1; SMN2NPC1PLAAT3PLAAT5 | |
| SCHEMBL8550897 | 0.76 | SMN1; SMN2 (0.36) | RAB9ASMN1; SMN2NPC1PLAAT3PLAAT5 | |
| SCHEMBL8144690 | 0.76 | HTT (0.40) | SMN1; SMN2KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL8551386 | 0.75 | MAPT (0.40) | SMN1; SMN2KMT2AMAPTMEN1GAA | |
| SCHEMBL1508505 | 0.74 | MEN1 (0.45) | RAB9ASMN1; SMN2NPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |