Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919985 | 0.84 | MEN1 (0.64) | OGAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL1307345 | 0.84 | DRD2 (0.55) | OGAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL1308281 | 0.82 | MEN1 (0.65) | OGAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL1023091 | 0.81 | MEN1 (0.58) | OGAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL8136256 | 0.81 | NOS2 (0.57) | MEN1KMT2AHTTGAAKDM4E | |
| SCHEMBL30499260 | 0.80 | HTT (0.60) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL14427198 | 0.79 | KMT2A (0.68) | OGAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL8152803 | 0.79 | DRD2 (0.59) | OGAALDH1A1GAAADORA2AADORA1 | |
| SCHEMBL10245567 | 0.79 | MEN1 (0.60) | OGAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL19231572 | 0.79 | MEN1 (0.60) | OGAMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119741-A2 | 3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2008-10-09 | — | — | WO | disclosed |