Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148497 | 0.82 | TRPM8 (0.39) | ALDH1A1KCNA5LMNATRPM8TRPA1 | |
| SCHEMBL8643093 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KCNA5LMNATRPM8TRPA1 | |
| SCHEMBL8146933 | 0.74 | ALDH1A1 (0.38) | ALDH1A1KCNA5LMNATRPM8TRPA1 | |
| SCHEMBL8147103 | 0.72 | EPHX1 (0.42) | ALDH1A1KCNA5LMNATRPM8TRPA1 | |
| SCHEMBL8639031 | 0.72 | TRPM8 (0.40) | ALDH1A1KCNA5LMNATRPM8TRPA1 | |
| SCHEMBL8639602 | 0.71 | FDPS (0.31) | — | |
| SCHEMBL8141083 | 0.70 | TRPM8 (0.38) | ALDH1A1KCNA5LMNATRPM8TRPA1 | |
| SCHEMBL30904661 | 0.68 | TRPM8 (0.48) | ALDH1A1KCNA5LMNATRPM8TRPA1 | |
| SCHEMBL5981079 | 0.68 | TRPM8 (0.48) | ALDH1A1KCNA5LMNATRPM8TRPA1 | |
| Bicarbonate SCHEMBL29029158 | 0.67 | EPHX1 (0.45) | KCNA5TRPM8TRPA1EPHX1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000013690-A1 | EXOCYCLIC-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 2000-03-16 | — | — | WO | claimed |
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | claimed |
| WO-2000013690-A1 | EXOCYCLIC-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 2000-03-16 | — | — | WO | disclosed |
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |