Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 3/20 | 0.35 |
| ▸ | GRM6 | O15303 | 3/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147974 | 0.85 | ADRB2 (0.40) | ADRB2ADRB1ADRB3GRIN2BGRM8 | |
| SCHEMBL1597063 | 0.76 | CYP1A2 (0.48) | ADRB2ADRB1ADRB3SHBGMEP1B | |
| SCHEMBL2299572 | 0.75 | SHBG (0.55) | ADRB1ADRB3GRIN2BSHBGESR1 | |
| SCHEMBL3279640 | 0.74 | ADRB2 (0.38) | ADRB2ADRB1ADRB3SHBGMEP1B | |
| SCHEMBL7916578 | 0.72 | ADRB2 (0.46) | ADRB2ADRB1ADRB3SHBGESR1 | |
| SCHEMBL1596134 | 0.70 | CA1 (0.48) | SHBGESR1ESR2 | |
| SCHEMBL1596154 | 0.70 | SHBG (0.37) | ADRB2ADRB1ADRB3SHBGESR1 | |
| SCHEMBL25147626 | 0.70 | ADRB2 (0.44) | ADRB2ADRB1ADRB3SHBGHKDC1 | |
| SCHEMBL836444 | 0.70 | SLC6A2 (0.41) | GRIN2BHKDC1 | |
| SCHEMBL20831638 | 0.69 | ADRB2 (0.37) | ADRB2ADRB1ADRB3SHBGESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147169-A | LOW TEMPERATURE CURING MIXTURE OF REACTIVE BASE RESIN AND A CLATHRATE COMPRISING A TETRAKISPHENOL HOSTING A CURING AGENT OR CURING CATALYST; STORAGE STABILITY, CORROSION RESISTANCE, ADHESION | KANSAI PAINT CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |