Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TPH1 | P17752 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153598 | 0.78 | PDE4A (0.43) | ALDH1A1LMNAKDM4ESMN1; SMN2PDE4A | |
| SCHEMBL6801438 | 0.77 | LMNA (0.43) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL10770013 | 0.76 | LMNA (0.43) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8150286 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4ERAB9AGAA | |
| SCHEMBL6801066 | 0.71 | LMNA (0.37) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL6800912 | 0.69 | ADORA1 (0.39) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9824594 | 0.69 | LMNA (0.53) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL9825107 | 0.69 | LMNA (0.53) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL9824232 | 0.69 | LMNA (0.42) | ALDH1A1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL9824269 | 0.69 | LMNA (0.42) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028950-A1 | NOVEL 7-SUBSTITUTED QUINAZOLIN-2,4-DIONES USEFUL AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999021840-A1 | NOVEL 7-SUBSTITUTED QUINAZOLIN-2,4-DIONES USEFUL AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-05-06 | — | — | WO | disclosed |