Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8139335 | 0.82 | CYP1A2 (0.45) | ALDH1A1KMT2AMEN1LMNAPOLB | |
| SCHEMBL6803985 | 0.76 | KMT2A (0.48) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL8145704 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL6802147 | 0.75 | KMT2A (0.49) | ALDH1A1KMT2AMEN1GAALMNA | |
| Piperidine SCHEMBL8145697 | 0.72 | LMNA (0.45) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL6799416 | 0.70 | THRB (0.46) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL609448 | 0.69 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDKDM4EBRD4 | |
| SCHEMBL9824152 | 0.69 | DRD3 (0.50) | ALDH1A1KMT2AMEN1GAAPOLB | |
| SCHEMBL2933050 | 0.69 | KDM4E (0.48) | ALDH1A1LMNAHPGDKDM4EBRD4 | |
| SCHEMBL30539983 | 0.69 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028950-A1 | NOVEL 7-SUBSTITUTED QUINAZOLIN-2,4-DIONES USEFUL AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999021840-A1 | NOVEL 7-SUBSTITUTED QUINAZOLIN-2,4-DIONES USEFUL AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-05-06 | — | — | WO | disclosed |