Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947825 | 0.87 | NPSR1 (0.62) | NPSR1DGAT1KCNH2MAPTKDM4E | |
| SCHEMBL5512134 | 0.84 | DYRK3 (0.42) | NPSR1DGAT1KCNH2MAPTKDM4E | |
| SCHEMBL14669313 | 0.80 | NPSR1 (0.45) | NPSR1DGAT1KCNH2MAPTKDM4E | |
| SCHEMBL7018825 | 0.79 | TRPA1 (0.53) | NPSR1MAPTKDM4EHPGDPOLB | |
| SCHEMBL20494892 | 0.77 | DGAT1 (0.42) | NPSR1DGAT1KCNH2MAPTKDM4E | |
| SCHEMBL10295 | 0.77 | NPSR1 (1.00) | NPSR1MAPTKDM4EHPGDPOLB | |
| SCHEMBL29353981 | 0.77 | NPSR1 (1.00) | NPSR1MAPTKDM4EHPGDPOLB | |
| SCHEMBL5681855 | 0.76 | NPSR1 (0.59) | NPSR1DGAT1KCNH2MAPTKDM4E | |
| SCHEMBL22649095 | 0.76 | NPC1 (0.67) | DGAT1KCNH2MAPTKDM4EHPGD | |
| SCHEMBL30341867 | 0.76 | PARP1 (0.54) | NPSR1MAPTKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6219946-A | — | — | None | — | — | JP | disclosed |
| EP-0667861-B1 | 2-TRIFLUOROMETHYL BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 2000-07-19 | — | — | EP | disclosed |
| US-5863933-A | NEMATOCIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5656649-A | PESTICIDE, INSECTICIDES, NEMATOCIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-12 | — | — | US | disclosed |
| US-5482956-A | ANTIPROTOZOA AGENTS FOR ANIMALS OR INSECTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-09 | — | — | US | disclosed |
| EP-0667861-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| JP-H06219946-A | USE OF SUBSTITUTED BENZIMIDAZOLE | BAYER AG | 1994-08-09 | — | — | JP | disclosed |
| WO-1994011349-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| EP-0597304-A1 | Use of substituted benzimidazoles | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |