Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3064583 | 0.85 | EGFR (0.40) | ALDH1A1KDM4EMEN1KMT2AEGFR | |
| SCHEMBL27615607 | 0.80 | KDM4E (0.39) | HCAR2FFAR3HCAR3ALDH1A1MAPT | |
| SCHEMBL21289229 | 0.76 | BACE1 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL7631700 | 0.75 | MAOA (0.40) | ALDH1A1MAPTKDM4ETHRBL3MBTL1 | |
| SCHEMBL12457244 | 0.74 | TYR (0.48) | ALDH1A1MAPTGPR84MEN1KMT2A | |
| SCHEMBL13951478 | 0.73 | EGFR (0.33) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL21569772 | 0.72 | TYR (0.42) | ALDH1A1MAPTKDM4EGPR84MEN1 | |
| SCHEMBL201692 | 0.72 | NPC1 (0.57) | EGFR | |
| SCHEMBL456005 | 0.72 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4ETHRBPKM | |
| SCHEMBL8914968 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4ETHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000005304-A1 | METHOD FOR REDUCING ODOR DURING PROCESSING OF FLAME RETARDANT POLYMERS | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-02-03 | — | — | WO | disclosed |