SCHEMBL8147339

SCHEMBL8147339

Nc1cc(Oc2c(F)c(Oc3cc(N)c(F)c(F)c3)c(C(F)(F)F)c(C(F)(F)F)c2F)cc(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
HSP90AA1 P07900 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8151920 0.90 POLB (0.31) POLBHSP90AA1MAPT
SCHEMBL8144265 0.83 MAPT (0.38) POLBHSP90AA1MAPT
SCHEMBL8143651 0.82 RAB9A (0.30)
SCHEMBL8144453 0.81 MAPT (0.36) POLBHSP90AA1MAPT
SCHEMBL8151250 0.81 KIF11 (0.31) POLBHSP90AA1MAPT
SCHEMBL8138972 0.80
SCHEMBL8145723 0.79 POLB (0.31) POLBHSP90AA1MAPT
SCHEMBL8152495 0.79 RAB9A (0.30)
SCHEMBL8146256 0.78 L3MBTL1 (0.32) HSP90AA1MAPT
SCHEMBL8138576 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103860-A LOW DIELECTRIC CONSTANT, EXCELLENT TRANSPARENCY, LOW HYGROSCOPICITY AND EXCELLENT PROCESSABILITY; SUBSTRATE FOR AN OPTICAL DISK, A PICK-UP LENS, A PLASTIC SUBSTRATE FOR A LIQUID CELL AND A PRISM MITSUI CHEMICALS, INC. (JP) 2000-08-15 US disclosed
US-5990261-A Organic optical component MITSUI CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0826717-A1 An organic optical component MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-03-04 EP disclosed