Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7376480 | 0.87 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2NPSR1PKMTSHR | |
| SCHEMBL7371765 | 0.84 | ME3 (0.54) | ALDH1A1SMN1; SMN2GAAMAPTGFER | |
| SCHEMBL8135239 | 0.84 | ACHE (0.45) | ALDH1A1TSHRUSP2 | |
| SCHEMBL8143954 | 0.79 | ACACB (0.47) | ALDH1A1SMN1; SMN2GAAHPGD | |
| Trifluoroacetic Acid SCHEMBL7376343 | 0.78 | ME3 (0.48) | ALDH1A1SMN1; SMN2GAAMAPTGFER | |
| SCHEMBL21815373 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TSHRUSP2 | |
| SCHEMBL7371906 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TSHRGAAMAPT | |
| SCHEMBL8141371 | 0.76 | POLB (0.46) | MAPT | |
| SCHEMBL8148488 | 0.75 | MLNR (0.45) | ALDH1A1TSHRUSP2 | |
| SCHEMBL4035778 | 0.75 | NPSR1 (0.70) | ALDH1A1NPSR1TSHRCHRM4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |