Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 5/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7376483 | 0.88 | MLNR (0.46) | MLNRMAPKAPK2LMNAKMT2ATSHR | |
| SCHEMBL8143948 | 0.87 | MAPKAPK2 (0.48) | MAPKAPK2ITGB3ITGA2BALOX15LMNA | |
| SCHEMBL8144006 | 0.86 | MLNR (0.43) | MLNRMAPKAPK2LMNATSHRPDK2 | |
| SCHEMBL7371765 | 0.77 | ME3 (0.54) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL8148485 | 0.75 | ALDH1A1 (0.48) | TSHRUSP2ALDH1A1 | |
| SCHEMBL7371906 | 0.75 | ALDH1A1 (0.46) | MAPKAPK2ITGB3ITGA2BALOX15MEN1 | |
| SCHEMBL8143954 | 0.75 | ACACB (0.47) | ALDH1A1 | |
| SCHEMBL8143170 | 0.74 | MAPT (0.43) | MLNRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL3246144 | 0.73 | MAPKAPK2 (0.53) | MAPKAPK2LMNATSHRUSP2ALDH1A1 | |
| SCHEMBL8135239 | 0.72 | ACHE (0.45) | ITGB3ITGA2BALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |