Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | ME2 | P23368 | 1/20 | 0.47 |
| ▸ | ME1 | P48163 | 1/20 | 0.47 |
| ▸ | ME3 | Q16798 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238946 | 0.85 | POLB (0.53) | ALOX5POLBNAMPTFAAHEPHX2 | |
| SCHEMBL8134080 | 0.81 | POLB (0.53) | POLBNAMPTFAAHCA12CA2 | |
| Trifluoroacetic Acid SCHEMBL7376456 | 0.75 | GLA (0.48) | POLBNAMPTFAAHCA12CA2 | |
| SCHEMBL12005896 | 0.74 | ALDH1A1 (0.57) | POLBMAPTGLAMEN1KMT2A | |
| SCHEMBL3697173 | 0.74 | NAMPT (0.70) | NAMPT | |
| SCHEMBL9234923 | 0.73 | TSHR (0.48) | ALOX5POLBNAMPTFAAHEPHX2 | |
| SCHEMBL533096 | 0.72 | ALDH1A1 (0.62) | NAMPTME3MAPTMEN1KMT2A | |
| SCHEMBL6271335 | 0.71 | POLB (0.66) | POLBNAMPTFAAHCA12CA2 | |
| SCHEMBL7371765 | 0.71 | ME3 (0.54) | POLBME3MAPTMEN1KMT2A | |
| SCHEMBL9237266 | 0.71 | FAAH (0.72) | POLBNAMPTFAAHCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |