SCHEMBL8149207

SCHEMBL8149207

CON=CC(=O)N(C)c1ccccc1CON=C(C)C(=NOC)C(C)=NOC

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.34
KDM4E B2RXH2 1/20 0.32
HIF1A Q16665 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31
SNCA P37840 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6429882 0.78
SCHEMBL8646153 0.77 LMNA (0.38) KDM4ELMNASNCA
SCHEMBL8157946 0.77 PTGS2 (0.40) PTGS2KDM4EHIF1AMEN1KMT2A
SCHEMBL8157948 0.77 PTGS2 (0.40) PTGS2KDM4EHIF1AMEN1KMT2A
SCHEMBL7464103 0.76 UTS2R (0.33) PTGS2HIF1AMEN1KMT2ALMNA
SCHEMBL7174055 0.76
SCHEMBL8399047 0.76 GRM5 (0.39) KDM4EHIF1ALMNA
SCHEMBL8396067 0.75 NISCH (0.38) KDM4EHIF1AMEN1KMT2ASNCA
SCHEMBL8163432 0.75 PTGS2 (0.52) PTGS2KDM4EHIF1AMEN1KMT2A
SCHEMBL8396050 0.74 RECQL (0.44) KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6037378-A OXIMINATION; FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-03-14 US disclosed