SCHEMBL8149286

SCHEMBL8149286

CC(=O)Oc1ccc(-c2ccc(CC(C)OC(C)=O)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.54
POLB P06746 2/20 0.48
KMT2A Q03164 1/20 0.48
GAA P10253 3/20 0.47
LMNA P02545 2/20 0.47
PPARG P37231 6/20 0.44
PPARA Q07869 5/20 0.44
ELANE P08246 1/20 0.44
MAPT P10636 3/20 0.43
TDP1 Q9NUW8 1/20 0.43
MMP12 P39900 1/20 0.43
LDHA P00338 1/20 0.42
HPGD P15428 1/20 0.42
ALDH1A1 P00352 1/20 0.41
HSP90AA1 P07900 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8716757 0.85 MMP12 (0.56) GAALMNAPPARGPPARAMMP12
SCHEMBL962571 0.85 TSHR (0.47) LMNAMAPTMMP12LDHAALDH1A1
SCHEMBL8162606 0.84 HSD17B10 (0.53) HSD17B10POLBKMT2AGAALMNA
SCHEMBL8155949 0.83 SMN1; SMN2 (0.50) HSD17B10KMT2ALMNAPPARGPPARA
SCHEMBL8156103 0.82 HSD17B10 (0.49) HSD17B10POLBKMT2AGAALMNA
SCHEMBL7784092 0.82 LDHA (0.64) PPARGPPARALDHAALDH1A1
SCHEMBL16710518 0.82 LDHA (0.64) PPARGPPARALDHAALDH1A1
SCHEMBL9124146 0.82 CA12 (0.44) POLBKMT2AGAALMNAMAPT
SCHEMBL10743703 0.81 HSD17B10 (0.50) HSD17B10POLBKMT2AGAALMNA
SCHEMBL159833 0.80 PTGS2 (0.55) POLBKMT2ALMNAELANEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0806417-B1 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL CO (JP) 2000-03-08 EP disclosed
US-5741438-A Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as an effective component, and liquid crystal element using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-04-21 US disclosed
US-5693251-A LIQUID CRYSTAL DISPLAYS; HIGH SPEED RESPONSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-02 US disclosed
EP-0806417-A1 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-12 EP disclosed
US-5389293-A Light switches SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-02-14 US disclosed
EP-0395390-B1 Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same SUMITOMO CHEMICAL CO (JP) 1994-09-28 EP disclosed
EP-0360622-A2 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-28 EP disclosed